PHYSICAL EVALUATION OF RED GINGER EXTRACT (ZINGIBER OFFICINALE ROSC. VAR. RUBRUM) CREAM OF 10% AND 20% CONCENTRATION TO REDUCE LOW BACK PAIN FOR PREGNANT WOMEN IN SECOND AND THIRD OF TRIMESTERS
Keywords:Cream, Red Ginger, Pain
Objective: The purpose of this study was evaluated the physical properties of the cream of red ginger extract (Zingiber officinale Rosc var. Rubrum), which is safe for pregnant women in helping pregnant women in the 2nd and 3rd trimesters to reduce low back pain.
Methods: The physical properties of red ginger extract (Zingiber officinale Rosc. var. Rubrum) cream was evaluated by using 2 activities, namely evaluation of creams consisting of organoleptic, pH, viscosity, spreadability and Homogeneity test, then continued with phytochemical screening, which consisted of an examination of alkaloids and examination of steroids.
Results: The evaluation results of making red ginger extract cream (Zingiber officinale Rosc. var. Rubrum) with a concentration of 10% and 20% meet al. l the requirements of the physical properties of the cream such as organoleptic test (smell, color, shape and texture are the same), pH test formula 1 (7.7980±0.13700), formula 2 (7.6060±0.9659), viscosity test formula 1 (22845.8440±12747.09092), formula 2 (39040.7480±206000.08235), dispersion test formula 1 (2.9400±0.25100-3.2200±0.41473), formula 2 (2.7600±0.23022-3.3100±0.17464) and homogeneity test on both formulas (homogeneous). Red ginger extract cream contains alkaloids from phytochemical screening results.
Conclusion: Red ginger extract cream (Zingiber officinale Rosc. var. Rubrum) with concentrations of 10% and 20% fulfills all the requirements for the physical properties of the cream and has the potential to be applied to pregnant women in the 2nd and 3rd trimesters who experience low back pain.
Susila AH, Sumarno S, Sli DD. Effect of ginger extract (Zingiber officinale Rosc.) on reducing signs of inflammatory erythema in white rats (Rattus norvegicus) wistar strain with second-degree burns. FKUB Health Mag. 2014 Dec 4;1:214-22.
Sadikim RY, Sandhika W, Saputro ID. Effect of red ginger extract (Zingiber officinale var. rubrum) on the number of macrophages and blood vessels in clean wounds of male mice (Mus musculus) (experimental research on experimental animals). Period Skin Sex Health Sci. 2018 Aug 2;30:121-7.
Syapitri H. Ginger compress is efficacious in reducing pain intensity in rheumatoid arthritis sufferers. Pearl J Nurs. 2018 Jan 1;1:57-64.
Yuniarti EV, Windartik E, Akbar A. Effect of red ginger compress to decrease the scale of pain gout arthritis patients. Int J Sci Technol. 2017 Oct 10;6:133-7.
Ashraf K, Sultan S, Shah SAA. Phychemistry, phytochemical, pharmacological and molecular study of zingiber officinale roscoe: a review. Int J Pharm Pharm Sci. 2017 Sep 27;9(10):8-16. doi: 10.22159/ijpps.2017v9i11.19613.
Febriani A, Maruya IM, Sapitri ATW. Analgesic activity test of vanishing cream extract of red ginger (Zingiber officinale Rosc. var. rubrum) in male mice (Mus musculus). In: the 58th National Seminar on Indonesian Medicinal Plants and Traditional Health Services POKJANAS TOI; 2020.
Al Mansur FA, Djajadisastra J, Hanani E. Formulation and benefit test of red ginger oil and clove oil cream against menstrual pain. Indonesian J Nurs. 2017 Nov 3;20:139-47.
Astuti D, Puspitasari I. Comparison of the use of lavender oil and ginger oil in back massage on reduction of labor pain. Matern Sci J. 2017 Oct 2;2:92-101.
Lem HW, Lee AC. The effectiveness of ginger compress on non-specific low back pain. J Fundam Appl Sci. 2017 Nov 10;9(6S):1173-86.
Ugandar RE, Deivi KS. Formulation and evaluation of natural palm oil-based vanishing cream. Int J Pharm Sci Res. 2013 Sep 1;4:3375-80.
Husin F, Irianti B, Halida EM, Duhita F, Prabandari F, Yulita N, Yulianti N, Hartiningtiyaswati S, Anggraini Y. Evidence-based maternity care. Jakarta; 2014.
Febriani Y, Riasari H, Winingsih W, Aulifa DL, Permatasari A. The potential use of red ginger (Zingiber officinale Roscoe) dregs as analgesic. Indonesian. J Pharm Sci Technol. 2018 Mar 24;1:57-64.
Rahmadani S, Sa’diah S, Wardatun S. Optimization of red ginger (Zingiber officinale Roscoe) extraction by maceration method. Stud Online J (JOM) Pharm. 2015 Nov 18;1(1).
Kumari I, Kaurav H, Chaudhary G. Hedychium spicatum buch-ham. (Kuchri), a treasure house of essential oils. Int J Curr Pharm Sci. 2021;13:25-31. doi: 10.22159/ ijcpr.2021v13i4.42738.
Soedirman I, Astuti IY, Kristanti K. Effect of ointment base on physical properties and primary irritation of red ginger (Zingiber officinale Roxb.) ethanol extract. Pharm Pharm J Indonesian. 2009 Apr 1;6:45-57.
Sangande MM, Buang A, Rivai R. Cream formulation of red ginger (Zingiberis officinale var. rubrum) extract using glycerin ointment base and anti-inflammatory effectiveness test against mice (Mus musculus). Phyto Medicine J Pharm Sci. 2021 Jan 2;12:73-85.
Supu RD, Diantini A, Levita J, Red G. (Zingiber officinale var. rubrum): its chemical constituents, pharmacological activities and safety. Phytopharmacol Sci J Pharm. 2018 Jun 1;8.
Rahayu RD, Sugita S. The effectiveness of giving lavender and ginger aromatherapy to reducing the frequency of nausea vomiting in first-trimester pregnant women in BPM Trucuk Klaten. J Midwifery Trad Health. 2018 Mar 1;3:19-26.
Azkiya Z, Ariyani H, Nugraha TS. Evaluation of the physical properties of red ginger (Zingiber officinale Rosc. var. rubrum) extracts cream as an anti-pain. J Curr PharmSci. 2017 Sep 1;1:12-8.
Farage MA, Hood W, Berardesca E, Maibach H. Intrinsic and extrinsic factors affecting skin surface pH pH of the skin: Issues and challenges. Curr Probl Dermatol. 2018;54:33-47. doi: 10.1159/000489516, PMID 30130773.
Ainaro EP, Gadri A, Priani SE. Gel mask preparation formulation. Curr PharmSci. 2015;1:86-95.
Faradisa H, Cahyani MD, Rosyidi VA, Hidayat MA, Ningsih IY. The formulation of ginger oil nanoemulsions of three varieties of ginger (Zingiber officinale Rosc.) as a natural antioxidant. JRP. 2020;24(6):914-24. doi: 10.35333/JRP.2020.251.
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